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Inactivation of FMDV in Milk

FMDV in Milk Components
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Survival of FMD virus in the environment is temperature dependent:
At optimal pH (7.2 - 7.6)
Temperature (ºC)    Survival
4                               
1 year
22                             
8-10 weeks
37                             
10 days
56                             
< 30 minutes
examples of virus survival in different conditions :
Conditions Survival
Dry faeces 14 days
Urine 39 days
Slurry 6 months
Ground Summer 3 days
Winter 28 days
Survival of FMD virus is pH dependent:
pH (4ºC) Inactivation time
2 1 min
4 2 min
5.5 30 min
5.8 18 hours
11 2 hours
12 2.5 min
13 2.5 min
Milk
Experiments on survival of FMD virus in milk and milk components from infected cattle have demonstrated that
pasteurisation at temperatures between 72ºC and 95ºC for 15-17 seconds fails to sterilise completely. Virus
can also survive further heat treatment at 65ºC for 1 hour.
Heating of infected milk to between 100ºC and 138ºC for 2-3 seconds fails to inactivate infection, but no
virus can be detected, by animal inoculation, after treatment at 148ºC for 2-3 seconds.
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