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Disease Prevention

Vaccination

 

Vaccine Banks

 

 

FMD control must be considered on a regional basis. This fact was recognised most recently by the European Union, and was the motivation for the changes in European FMD control strategy before the introduction of the Single Market on 1 January 1993.

In the first instance FMD-free countries would attempt to control an outbreak of FMD through 'stamping out', with slaughter of affected and in-contact susceptible livestock and the imposition of movement restrictions. However, in certain circumstances, where an outbreak threatened to become extensive, in densely populated pig production areas where there was a high-risk of airborne spread or for welfare reasons, strategic 'ring' vaccination could be used. Therefore, FMD-free countries now maintain Emergency FMD Vaccine Banks, often cooperatively with other countries of similar FMD status.

These banks store FMD vaccine, either pre-formulated or more commonly as frozen, concentrated antigen. The essential elements of the emergency FMD vaccine banks are immediate access to highly potent vaccines from antigens of known potency and spectrum of activity, a facility for rapid re-formulation of the vaccines under Good Manufacturing Practice (GMP) conditions and a capacity for efficient bottling, labelling and despatch. The aim of the 'ring' vaccination would be to reduce the risk of further spread of the outbreak and to dampen down the amount of virus generated. Decisions would be made on when and where to vaccinate with the assistance of the airborne prediction models and expert systems available to the epidemiology team.

The objective of a vaccine bank is to guarantee rapid access to vaccine of known quality. In the case of FMD this is especially important because of the ability of the disease to spread rapidly and the recent contraction of the FMD vaccine market. There are three international vaccine banks in existence and many national banks around the world. All member countries of these banks are FMD-free and have a 'stamping out' policy for FMD control in the first instance. Member countries would only resort to emergency vaccination when an outbreak threatened to become extensive due to livestock density or geographical considerations, or where valuable breeding stock was involved. .

   


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