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Foot and Mouth Disease (FMD)

 

 

 

AETIOLOGY

A virus of the family Picornaviridae, genus Aphthovirus.
Seven immunologically distinct serotypes: A, O, C, SAT1, SAT2, SAT3, Asia1

Temperature: 

Preserved by refrigeration and freezing and progressively inactivated by temperatures above 50°C

pH:

Inactivated by pH <6.0 or >9.0

Disinfectants: 

Inactivated by sodium hydroxide (2%), sodium carbonate (4%), and citric acid (0.2%). Resistant to iodophores, quaternary ammonium compounds, hypoclorite and phenol, especially in the presence of organic matter

Survival: 

Survives in lymph nodes and bone marrow at neutral pH, but destroyed in muscle when is pH <6.0 i.e. after rigor mortis. Can persist in contaminated fodder and the environment for up to 1 month, depending on the temperature and pH conditions

 

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