|
|
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Incubation period is 2-14 days
-
Pyrexia, anorexia, shivering, reduction in milk production
for 2-3 days, then
-
smacking of the lips, grinding of the teeth, drooling,
lameness, stamping or kicking of the feet: caused by vesicles
(aphthae) on buccal and nasal mucous membranes and/or between
the claws and coronary band
-
after 24 hours: rupture of vesicles leaving erosions
-
vesicles can also occur on the mammary glands
-
Recovery generally occurs within 8-15 days
-
Complications: tongue erosions, superinfection of lesions,
hoof deformation, mastitis and permanent impairment of milk production,
myocarditis, abortion, death of young animals, permanent loss of weight,
loss of heat control ('panters')
-
Vesicles or blisters on the tongue, dental pad, gums,
cheek, hard and soft palate, lips, nostrils, muzzle, coronary bands,
teats, udder, snout of pigs, corium of dewclaws and interdigital spaces
-
Post-mortem lesions on rumen pillars, in the myocardium,
particularly of young animals (tiger heart)
| Identification of the agent |
- ELISA
- Complement fixation test
- Virus isolation: inoculation of primary bovine
thyroid cells and primary pig, calf and lamb kidney cells; inoculation
of BHK-21 and IB-RS-2 cell lines; inoculation of mice
|
Serological tests |
|
|
(prescribed tests in the Manual) |
|
-
1 g of tissue from an unruptured or recently ruptured
vesicle. Epithelial samples should be placed in a transport medium
which maintains a pH of 7.2-7.4 and kept cool (see Manual)
-
Oesophageal-pharyngeal fluid collected by means of a
probang cup Probang samples should be frozen to below -40°C immediately
after collection
| NB!! |
Special precautions are required when sending
perishable suspect FMD material within and between countries.
See Manual, Chapter 1.4. |
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